Genetic Testing Solutions 2
The Virant Diagnostics Genetic Laboratory uses cutting-edge science and technology to provide accurate genomic testing.
About Our Genetic Laboratory
The Virant Diagnostics Genetic Laboratory is made up a team of experienced geneticists and molecular biologists. Our specialized knowledge and advanced laboratory equipment allows us to provide the highest quality molecular diagnostic services. We use a proprietary bioinformatics pipeline with the most up-to-date and relevant data to analyze your samples. Virant Diagnostics is ready to work with your team to improve patient care.
Currently, our Genetics Test Menu is primarily focused on the pathogenesis of angioedema at the genetic level. Please visit our Angioedema Page for more information on angioedema pathophysiology and complement assays.
Create an order and view results now.
- Create an order from our Client Portal or via Requisition Form
- Please be sure to obtain patient consent for genetic testing
- Access secure, encrypted results from our Client Portal
Our Genetic Test Menu
Individual Gene Testing
Angioedema with C1 inhibitor deficiency
Angioedema with normal C1 inhibitor genes
Targeted Testing
Angioedema with C1 inhibitor deficiency
- SERPING1 Sequencing of the coding region +/- 10 base pairs for exons 2-8 with exon duplication/deletion testing
- OMIM 106100
Angioedema with normal C1 inhibitor genes
- Sequencing of known mutations in 6 OMIM related angioedema genes:
- F12
- KNG1
- ANGPT1
- PLG
- MYOF
- HS3ST6
- We also offer duplication/deletion testing for F12 gene, exons 1-12, except exon 3
- Click here for details and descriptions for each gene on this panel
Targeted Testing
- Targeted testing for a SERPING1 coding variant, or variants listed in the nlC1INH table that have been previously identified in a family member
- Clinical confirmation of variants found in a research laboratory

Click here for references.
Small Panel Testing
nlC1INH Panel
Angioedema Panel
nlC1INH Panel
- All known HAE variants in the 6 genes associated with angioedema with normal C1 inhibitor function
- Genes tested:
- F12
- KNG1
- ANGPT1
- PLG
- MYOF
- HS3ST6
Angioedema Panel
- All 7 genes (SERPING1 and nlC1INH genes)
- Genes tested:
- SERPING1
- F12
- KNG1
- ANGPT1
- PLG
- MYOF
- HS3ST6
Large Panel Testing
Comprehensive Hereditary Angioedema (HAE) 77-gene Panel
Whole Exome Sequencing
Comprehensive Hereditary Angioedema (HAE) 77-gene Panel
- This gene panel sequences and analyzes 77 genes involved with complement, coagulation, and tissue kallikrein pathways
- Click here for details and descriptions for each gene on the panel
Whole Exome Sequencing
- Whole exome sequencing sequences in all protein-coding regions of the genome. Analysis reviews all identified variants along with relevant medical history to reveal diseases that a patient may have, develop, and/or pass down
- Must provide clinical information when submitting a sample
- Maternal and paternal samples in addition to proband samples are helpful