Angioedema Testing Solutions

Angioedema is a self-limited, transient, and localized swelling caused by extravascular leakage of fluid into the interstitial tissues commonly involving the subcutaneous and/or the submucosal tissues of the skin and upper respiratory and gastrointestinal tracts, respectively. Angioedema attacks can be acute, lasting hours to days, or chronic if recurrent. Symptoms may be troublesome, disabling, and even life-threatening. The swelling in angioedema is caused by increased vascular permeability, which is mediated by histamine or bradykinin. Bradykinin-mediated angioedema is not triggered by allergies, therefore treatment with antihistamines and steroids are ineffective.